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demonstrated that chronic IGF-1 overexpression in smooth muscle cells (SMCs) did not increase overall plaque extensiveness and exhibited features of stable plaques in Apoe -/- mice fed a Western diet (146)

Furthermore, the authors showed negative associations between low levels of DTAC, increased serum MDA concentrations and depression/anxiety

demonstrated that ganoderic acid D exhibits potent antisenescence effects against H 2 O 2 -induced premature senescence of human amniotic mesenchymal stem cells through the activation of PERK/Nrf2 signals [141]

Intralesional corticosteroid injection with 5 to 10 mg/mL of triamcinolone acetonide has been used as an adjunctive therapy to accelerate the resolution of early painful inflammatory nodules