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Cells of the renal tubules contain many of the same detoxification enzymes as liver cells (Jancova 2010)

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However, determination of high levels of total serum GGT activity is not specific to alcohol intoxication, [18] and the measurement of selected serum forms of the enzyme offer more specific information

Our screen also confirmed that depleting cell cycle progression activators such as CDK2 and CCNE1 increased sensitivity to palbociclib 18,25,26