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Glutaminase potentiates the Glycolysis in esophageal squamous cell carcinoma by interacting with PDK1

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229 As mentioned above, the intratumoral myeloid cells have vigorous glycolytic activity, but whether myeloid-derived lactate limits T cell effector functions, remains to be explored

In contrast, another study that specifically induced the death of AgRP and POMC neurons, profound metabolic disorders and obesity emerged (129) ( Figure 2 )

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