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doi: 10.1095/biolreprod.114.126680 56 LiuPShiJShengDLuWGuoJGaoLet al

GSK-3 acts upstream of fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2

Importantly, many of these effects can also be reproduced by exercise mimetics that target the corresponding molecular pathways

Mutations in GRM3 result in constitutive receptor activation, provide signals for cell proliferation and survival in melanoma [89], and are closely associated with invasive behavior [90]

Lipids are also easily subjected to oxidative modification by ROS with a particularly devastating process in lipid-rich brain tissue