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Most of these involve the stifle (knee) joint, where the cranial cruciate ligament, menisci, and articular cartilage work together and where the majority of canine orthopedic injuries occur: Cranial Cruciate Ligament Disease: The canine equivalent of human ACL tears, extremely common in medium to large breeds

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It has been reported that liposomal vaccines can carry both Th and cytotoxic T lymphocyte epitopes and activate both CD4 + and CD8 + T cells, producing specific anti-tumor immune response in mice models with therapeutic and preventive effects (Zamani et al., 2019
