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37 In terms of antimicrobial activity, berberine demonstrated strong effects against dysbiotic bacteria in IBS models, reducing the abundance of Escherichia/Shigella and Proteobacteria while enriching beneficial taxa such as Lactobacillus and Ruminococcus

Then, to verify the impact on ENS neuronal activity, intestinal preparations were subjected to electrical field stimulation (EFS) at increasing frequencies with constant voltage, to induce neuronal depolarization and consequent neurotransmitters release

VanItallie TB, Nufert TH

doi: 10.1097/00007611-198411000-00007 141 TobiMMoragARavidZChowersIFeldman-WeissVMichaeliYet al

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