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Inhibiting IRF7 may alleviate UC symptoms in DSS-induced mice by decreasing levels of TNF-, IL- 6, monocyte chemoattractant protein- 1, IL- 1, ROS, iron ions, and lipid peroxidation while increasing glutathione and GPX4 levels [73]
The bulk RNA-seq data from the GEO database verified the increase in CP mRNA expression
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