glutathione biosynthesis and mechanism of action Apoptosis glutathione: beyond an antioxidant Induction of glutathione biosynthesis by
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[in Italian] Altomare E, Colonna P, DAgostino C, et al

first, the N-terminal cysteine on Grx deglutathionylates PSSG via a thiol disulfide exchange reaction yielding PSH and a GrxSSG intermediate

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doi: 10.1146/annurev.food.112408.132746

Under high iron conditions, IRP2 is degraded, relieving its repression of ferritin/FPN translation and destabilizing TfR1 mRNA (41, 42)
