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Statistical analysis Data analysis was performed using IBM SPSS Statistics version 27.0 (IBM Corp.) and Microsoft Excel for statistical computations and data visualization

ATRA failed to exert an effect on the GS promoter and had no effect on Nrf2 or NFB expression

Reference data: PubChem

5.5 Conclusion and future direction Recognizing the limitations of conventional delivery routes in targeting the CNS, IN administration provides a non-invasive alternative that not only bypasses the BBB but also avoids hepatic first-pass metabolism

Platform 96-Well Microplate, Microcuvette Sample Type Serum, plasma, plant tissues, cell lysates, and biological fluids Components Assay Buffer, Chromogen, Substrate Storage Shipped at 4C