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On the primary functions of melatonin in evolution: mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals
Impairment of Nrf2/ARE signaling has been observed in HCV infection, leading to elevated ROS levels that can activate autophagy and facilitate HCV maturation and release 103,104
Pearson, W
Cytokine production was different in these animals suggesting that altered redox balance, particularly as a consequence of GSH changes could influence immune response
Moreover, a vitamin E diet is also associated with risk factors for neurodegenerative diseases such as PD (102)
