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18 Pathophysiological mechanisms involved in ischemic stroke As a hallmark of ischemic stroke, interrupted cerebral blood flow depletes the brain of oxygen and glucose, which leads to disrupted ATP synthesis and energy deficiency, as well as impaired ion homeostasis and acid-base imbalance

Magleby KL, Zengel JE (1982)

Visual changes often precede scale changes, especially when fat loss is accompanied by lean mass preservation

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E., Toni, I., Kessels, R