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Similar findings were made by Lee et al
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By binding to c-Met, dihexa activates signaling pathways that promote neuronal survival, stimulate neurogenesis, and enhance synaptogenesis
& Puvanakrishnan, R
However, 5-FU exerts general toxicity on normal proliferating cells due to 5-FdUTP and dUTP misincorporation into DNA and 5-FUTP into RNA 24
