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Cancer metabolism: fatty acid oxidation in the limelight

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It is also a co-factor for GPX4-mediated lipid detoxification 35 , and GPX4 activity is necessary for the survival of several tissues, including the liver 36 and kidney 37

The same group subsequently reported that BPC-157 modulates vasomotor tone by enhancing phosphorylation of Src, caveolin-1, and eNOS, and that the peptide reduces caveolin-1/eNOS binding a step that releases eNOS from caveolar inhibition and permits nitric oxide generation (Hsieh et al., 2020)
