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Researchers also explore broader, off-label areas such as recovery support after intense training, joint and connective-tissue strain, and gut comfort during periods of stress

doi: 10.1002/(sici)1097-4644(20000601)77:3 3.0.co;2-p

Ongoing trials Trials like NCT07328100 (intravenous coenzyme I for vascular aging, 2026 start) and NCT05243290 (oral NR in Gulf War Illness) continue to expand the human evidence base

separate strong acids or retinoids if irritation occurs

Without strengthening and mechanics retraining, symptoms may return
