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Further, stromal cells of endometriotic lesions do not express 17 -hydroxysteriod dehydrogenase type 2 thereby preventing the conversion of estradiol 2 to estradiol 1 , usually induced by progesterone (Bulun et al

doi: 10.1080/09637486.2016.1181156 55 HadiAAlizadehKHajianfarHMohammadiHMiraghajaniM

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Therefore, the urge to develop regional guidelines is extremely obvious
