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During ferroptosis, the iron can react with hydrogen peroxide and lipid peroxides to form reactive oxygen species or reactive oxygen species-like that can build up inside the cell, leading to lipid peroxidation, and ultimately, the breakdown of crucial cellular membranes and cell death (Jiang et al., 2021)

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This may raise the possibility that pain, an early symptom of COVID-19, could be diminished by the SARS-CoV-2 S-protein interaction with NRP1 323