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L-Glu Exposure Affects the Morphological Characteristics of Neurons Nine studies reported morphological alterations to neurons following L-Glu administration, with alterations to nuclear size, chromatin condensation, and nuclear fragmentation [51,53,55,62,66,74], as well as signs of toxicity, particularly as cell body shrinkage and dendritic retraction [51,53,54,55,68,70]

These findings have been similar across several smaller studies that have shown misunderstanding of GF labels and difficulties in determining the amount of gluten that is present in meals

10.1006/jmbi.1997.0959 241 SinghN.ChaputL.VilloutreixB

Relevance of Experimental Doses to Human Exposure A major challenge in interpreting the toxicological evidence on MNPs is the disconnect between the high, often acute, concentrations used in experimental models and the lower, chronic exposures experienced by humans in real-world settings

Kinetics of hemin distribution in plasma reveals its role in lipoprotein oxidation