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Besides this purely quantitative aspect, Frye et al[39] analyzed the acyl-carnitine profile of ASD patients, in a large cohort ( n = 213), these authors reported that 17% of children with ASD exhibited an elevation in short-chain and long-chain, but not medium-chain, acyl-carnitines

However, others have found that the odds ratio of APOE2/4 individuals is more similar to that of APOE4 carriers than APOE2 carriers [21], suggesting that the increased risk associated with APOE4 is more dominant than the protection offered by APOE2

Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia