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Through rational antigen design and adjuvant optimization, it may be possible to strategically induce trained immune states to support infection control, immune modulation, and even chronic disease intervention

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For example, we have shown that depleting GSH in young wild-type mice results in mitochondrial dysfunction and that correcting GSH deficiency in old wild-type mice lowers reverses mitochondrial impairment, lowers OxS and insulin resistance [29]

Improves feed conversion, weight gain, and reproductive performance in deficient livestock

To view a copy of this licence, visit About this article Cite this article Movahednasab, M., Dianat-Moghadam, H., Khodadad, S