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Resveratrol supplementation prevented the exercise-induced decrease in the reduced glutathione/oxidized glutathione (GSH/GSSG) ratio in the gastrocnemius muscle, attenuated the increase in xanthine oxidase, hypoxanthine, and xanthine activity and significantly reduced H 2 O 2 by 15% [146, 147]

10.1096/fj.06-6722com [DOI] [PubMed] [Google Scholar] 197.Fujii H, Li S-H, Szmitko PE, Fedak PWM, Verma S

Central to this approach are degrons, short amino acid motifs, typically 610 residues in length, that mark proteins for recognition by E3 ubiquitin ligases

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Tissues were homogenized in 510 mL of cold buffer (50 mM potassium phosphate, pH 7.5, 1 mM EDTA) per gram of tissue, followed by centrifugation at 10,000 g for 15 min at 4 C