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According to the guidelines of the International Pediatric Sepsis Consensus Conference 104 , neonatal sepsis is defined as a clinical syndrome characterized by the presence of both infection and systemic inflammatory response syndrome (SIRS) and can cause severe neurological complications due to brain infection, as well as secondary hypoxemia resulting from septic shock, pulmonary hypertension and severe lung disease

Moreover, it will be of critical importance to conduct a cohort research with a representative number of samples

Consequently, the number of cold-specific A fibers and heat-specific C fibers starts reducing from the epidermis, known as loss of intraepidermal nerve fibers, and loss of nociceptors has also been observed that will result in the hyperresponsive state of the remaining nociceptors (60)

& Saito, H

(2) model group (Model), mice were administered PBS and exposed to UVB