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Mitohormesis, an antiaging paradigm, in International review of cell and molecular Biology

VCP dysfunction disrupts ubiquitin-dependent protein turnover, leading to widespread proteostasis failure and aggregate accumulation

Consequently, cysteine availability and the resulting GCS activity are both pivotal for GSH re-synthesis and therefore provide an indication of the models potential to recover GSH levels 21

10.2217/bmm-2017-0109 19 FryeR

Huang and Li, 2013
