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In this cascade, the activation of caspase-1 within the inflammasome complex leads to the cleavage of gasdermin-D (GSDMD) and the precursors of interleukin-1 (IL-1) and interleukin-18 (IL-18), marking the cell for pyroptotic death (Martinon et al., 2002

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A synergistic, multitargeted approach may eventually transform this devastating disease into a controllable chronic one

Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis

An aura manifests itself, for example, in the form of very different neurological symptoms such as visual field defects, paresthesia and paresis [258, 259]
