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Description
The Metabolic Syndrome - a global challenge for prevention

We have previously shown that during continual stimulation, the early transient increase in succinate and itaconate leads to a transient increase in HIF-1 stability and level 11

Atzeni F, Popa CD, Nucera V, Nurmohamed MT

This means that working on cancer cells alone will not achieve the goal of completely eliminating the tumor and new treatment strategies should consider the TME, that is, the surrounding immune cell components

10.1039/c3mt20223b 57 HermansC.HammondJ
