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Caution is also advised in people with severe gastrointestinal motility disorders or a history of pancreatitis

This innovative medication mimics the GLP-1 hormone, effectively reducing appetite and promoting notable weight loss

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Aib Substitution: Alanine at position 8 is replaced by -aminobutyric acid to "hide" the cleavage site from DPP-4

However, the bioavailability of oral preparations is relatively low due to poor absorption of peptide drugs in the intestine, and some drugs may be destroyed during digestion