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In some people, this progresses to gastroparesis a condition in which the stomach fails to empty properly

The mesh terms enabled the search and identification of clinical studies that were related to the objectives of this review

Notably, although there was not a statistically significant increase in biliary disease among GLP-1 receptor agonist users in this study, the FDA 2 added warnings and precautions about acute cholecystitis and biliary disease to the label in late 2022 based on data from placebo-controlled RCTs as well as other observational data 3

Trends Endocrinol Metab 2016;27:427-38.ArticlePubMed 32

Findings The study included 484,467 individuals with AID who were eligible for anti-obesity medication therapy