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Description
In the GLP-1 group, 2.6% of babies were born with a major birth defect

Most reactions are mild to moderate in severity and tend to resolve spontaneously within a few days without requiring treatment discontinuation

However, in infants born to people with type 2 diabetes who took a second-line noninsulin antidiabetic medication including GLP-1 receptor agonists the study did not find a greater major congenital malformation risk compared to infants exposed to insulin

A 2021 update on the use of liraglutide in the modern treatment of Diabesity: A Narrative Review

We aimed to systematically retrieve all currently available RCTs of tirzepatide in individuals with type 2 diabetes and synthesise the evidence by means of clinically relevant meta-analyses for outcomes of efficacy and safety
