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The B class of GPCRs is a relatively small group of receptors but, nevertheless, one that is important in metabolic diseases such as diabetes and obesity (62)
Wider availability could depend on future price adjustments or more affordable alternatives, says Dr
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Although the lipidation of GLP-1 peptides can enhance their binding to albumin, significantly increasing their half-life (this is currently a widely adopted pharmacokinetic enhancement strategy for GLP-1 peptides), lipidation modification is not universally applicable
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