does glp-1 affect kidneys Design and discovery of a highly potent ultralong-acting and glucagon co-agonist for attenuating renal fibrosis Potential kidney-protective and other effects

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Abstract Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells that modulates glucose metabolism by controlling insulin excretion and glucagon secretion and inhibits gastric emptying leading to decreased food intake, thus limiting weight gain

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GLP-1 and GLP-2 orchestrate intestine integrity, gut microbiota, and immune system crosstalk