semaglutide muscle mass loss (GLP-1) Loss: Body Composition Changes and Findings Nutrition, exercise guidance with use

Several ongoing clinical trials are evaluating semaglutide specifically for alcohol use disorder, with results pending

Journal reference: Klausen, M

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Cotadutide (MEDI0382) is the most extensively developed dual GLP-1/glucagon receptor agonist, showing significant improvements in glucose control, BW (likely mediated by reduced energy intake rather than increased energy expenditure), hepatic fat, and albuminuria in a small RCT on patients with T2D and overweight or obesity 45,46