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A practical target many guidelines use is about 150 minutes of moderate activity a week, mixing cardio such as walking, swimming, or cycling with some resistance training to help preserve muscle

For instance, the phentermine-topiramate combination increases anxiety and depression

The introduction of tirzepatide, the first dual agonist targeting both the GLP-1R and the glucose-dependent insulinotropic polypeptide (GIP) receptor, represents a new frontier in incretin-based therapy (Syed, 2022

By month 4, over 85% of patients report minimal to no side effects

doi: 10.1038/nm.3009 44 CoskunTSloopKWLoghinCAlsina-FernandezJUrvaSBokvistKBet al