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However, large-scale, blinded placebo-controlled trials are lacking

Additionally, enteroendocrine cells are equipped with GPCRs and transporters to sense the macronutrients and release the appropriate hormones (Spreckley and Murphy, 2015)

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Insulin lispro, insulin aspart, and insulin glulisine have rapid onset of action and, ideally, should be given approximately 10-20 minutes before mealtime when blood glucose is in the target range, keeping in mind that if the meal is delayed, hypoglycemia may ensue

This retrospective, single-arm real-world study included a total of 364 patients with mild-to-moderate DKD who had been treated with GLP-1RAs for at least 6 months
