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Lets break it down: TRT can increase dopa

this is related to effects on gastric emptying and appetite

Originally approved to treat diabetes, these GLP-1 agonists have since made headlines not just for their ability to manage obesity but to also positively influence a host of other conditions, from cardiovascular risk and fatty liver disease to neurogenerative diseases

In Koboris propensity-matched endoscopy series, the prevalence of solid gastric contents rose ten-fold (0.5 % 5.4 %) among GLP-1RA users [8], mirroring IVF recovery-room anecdotes of unexpected regurgitation

The tight junctions between epithelial cells in the mouth are designed to keep large molecules out, which is exactly what a peptide this size qualifies as