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The most common side effects of phentermine include: Rapid heart rate Tingling in the hands or feet Dry mouth Sleeplessness Nervousness Constipation You should not take phentermine if you have heart disease, including valvular heart disease, heart failure or high blood pressure, seizure disorders, severe renal disease, an overactive thyroid, or glaucoma, or are pregnant, trying to become pregnant, or breastfeeding

The relationships disclosed by the authors did not influence the design, conduct, or interpretation of the data presented in this study

These symptoms are usually mild and manageable

This is largely attributed to the GIP component's role in adipose tissue health and the secondary effects of reduced caloric intake