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Eur J Prev Cardiol 25:495502 Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes

A recently reported full-length GCGRglucagon model based on the crystal structures of the GCGR 7TMD (Siu et al., 2013), the antibody-bound GCGR ECD (Koth et al., 2012), the GLP-1bound GLP-1R ECD (Underwood et al., 2010), and the N-capped conformation of PACAP (Inooka et al., 2001) offers a template for full-length GLP-1bound GLP-1R models (Fig