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A new Phase 2 trial at Johns Hopkins testing the GLP-1 drug pegsebrenatide in progressive MS may finally explain why adults on diabetes medications for a decade show measurably slower brain shrinkage

Women who are pregnant or nursing and individuals with health conditions or on medications should be especially careful before using the supplement

The more meaningful question is not: Do patients regain weight after stopping GLP-1s? It is: How should we transition patients from pharmacologic support to long-term weight maintenance? Obesity is a chronic disease

We further explore the potential actions of multi-agonist drugs as well as the mechanisms through which gut-brain communication can be used to achieve long-term weight loss without negative side effects

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