incretin mimetic agents glp 1 receptor agonists Incretins: How we got here, where we're at and what is coming next Structures of formulations of GLP-1

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Over the past decades, researchers overcame significant challenges such as the hormones very short half-life in the body to develop long-acting GLP-1 receptor agonist drugs

doi: 10.1038/nrgastro.2016.181 14 SodhiMRezaeianzadehRKezouhAEtminanM

In obesity medicine, the emphasis expands to include behavioral factors, long-term adherence, and patient motivation

a novel role of GLP-1 receptor agonists in cirrhotic cardiomyopathy

These findings highlight the importance of TREM2 in promoting microglia polarization to the M2 anti-inflammatory phenotype and alleviating cognitive dysfunction (Wu M