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This delayed gastric emptying is what makes GLP-1 therapy so effective for weight managementbut it can also reduce the natural muscular contractions (peristalsis) that move stool through your colon, leading to constipation

doi: 10.1136/bmjdrc-2021-002619

Itll take years of studying uptake, adherence, and clinical outcomes to get a better idea of how much value Wegovy, Ozempic, and their successors actually provide

Saxenda is administered via subcutaneous injection once daily

Lifestyle changes are key with or without using other strategies for managing weight, such as weight-loss medications or weight-loss surgery, also called metabolic and bariatric surgery