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Additionally, the mechanisms complement each other: as GLP-1 reduces appetite and improves insulin sensitivity, SGLT2 inhibitors independently lower blood glucose through renal elimination, creating a powerful combination that addresses both insulin resistance and glucose overload

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[DOI] [PubMed] [Google Scholar] 32.Abu Rached N., Gambichler T., Ocker L., Dietrich J.W., Quast D.R., Sieger C., Seifert C., Scheel C., Bechara F.G

1996;271:E808E813