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10.3390/nu11102376 [DOI] [PMC free article] [PubMed] [Google Scholar] Goel A., Boland C
Prolonged cAMP signaling and homologous desensitization Intuitively, reduced loss of surface GLP-1R with exendin-phe1 should permit greater access to extracellular ligand during continuous exposure, with fast recycling ensuring that the receptors are maintained in a sensitized state
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In some patients, this temporarily raises uric acid and can trigger a gout flare in the first few months
Each medication has unique advantages and potential drawbacks, and choosing the right one depends on individual health needs and goals
