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Diabetol Metab Syndr 15(1):218 Zhong P, Zeng H, Huang M, Fu W, Chen Z (2022) Efficacy and safety of once-weekly semaglutide in adults with overweight or obesity: a meta-analysis

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GLP-1R-mediated dopaminergic modulation may vary by drug class: in alcohol models, suppression of dopamine release is coupled with reduced locomotor sensitization [7,24], whereas in psychostimulant paradigms, GLP-1R activation primarily blunts drug-induced dopamine overflow without abolishing baseline dopaminergic tone [10]

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