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Notably, Escherichia coli supplementation has been shown to enhance Interleukin-22 (IL-22) production in granulosa cells, mitigate mitochondrial damage in PCOS mice through sex hormone restoration and ovarian tissue morphology improvement, suppress deleterious GM populations, and facilitate aminoglycan and nucleotide sugar metabolic pathways (42)
doi: 10.1038/s41598-019-38956-2
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