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Less common but more serious risks include pancreatitis (0.2-0.3% per year), gallbladder disease (1-2% per year), and acute kidney injury from severe dehydration

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Innovators held patent monopolies to recoup research and development costsestimated at $2.6 billion per successful drugwhile compounders operated in a niche, providing customized medications for individual patients with specific needs, such as allergies to excipients

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