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We collected blood to quantify drug plasma concentration and captured digital photos of rat skin at the MNs insertion sites to study skin irritation using criteria that are defined in Table 1 (SI)

Microglial activation plays a critical role in the pathogenesis of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyidine- (MPTP-) induced Parkinson's disease model and human Parkinson's disease [27]

2f, g), while it inhibited food intake at all time points in control wild-type (WT) C57BL/6J mice (Fig

After withdrawing the needle, apply firm pressure with a clean gauze pad for at least 2 minutes (longer for patients on blood thinners), but do not rub the area