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Both medications are stimulants that work by raising levels of dopamine and norepinephrine in the brain

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Less common but more serious side effects of GLP-1 agonists include: pancreatitis, an inflammation of the pancreas that causes abdominal pain gastroparesis, in which movement of food out of the stomach is slowed or stopped bowel obstruction, a blockage that keeps food from passing through the intestines gallstone attacks and bile duct blockage

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Januvia currently has no reports of interacting with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD)