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Interactions with Hormonal Treatments for Endometriosis Hormonal treatments for endometriosis, such as oral contraceptives, progestins, and GnRH agonists, are used to suppress the growth of endometrial tissue outside the uterus and alleviate symptoms
The follow-up duration of these studies was variable, ranging from 16 months in the PIONEER-6 trial to 8.6 years in the SUSTAIN- 6 trial

Due to these combined effects, semaglutide is increasingly used to treat type 2 diabetes, obesity, and related cardiovascular diseases
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Sympathetic activation may favor the development of hypertension and organ damage in obesity and lead to overt cardiovascular disease