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Patients were randomly assigned in a 2:1 ratio to receive darolutamide or placebo while continuing ADT.[39,40] The 3-year OS rate was 83% for patients who received darolutamide (95% CI, 80%86%) and 77% for patients who received placebo (95% CI, 72%81%).[39,40][Level of evidence A1] The darolutamide arm was also associated with longer metastasis-free survival (HR, 0.41

After washing, tissues were post-fixed in 2% osmium tetroxide, dehydrated in ethanol/propylene oxide and embedded in epoxy resin
Infants whose mothers have gestational diabetes are also more likely to develop dangerously low blood glucose levels soon after birth

Although glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter-2 (SGLT2) inhibitors are increasingly used as second-line agents, direct comparisons between these treatments are insufficient
