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Several large-scale trials, including the LEADER and SUSTAIN-6 studies, demonstrated reduced cardiovascular risk in patients at high baseline risk

The trial moved semaglutide from a weight loss tool into a recognised cardiovascular risk reduction therapy

Key Takeaways Semaglutides Indian patent expired on 20 March 2026, and generic versions now cost roughly 5090% less than branded Ozempic a big part of why the GLP-1 drugs cost in India has fallen so fast

A randomized controlled trial could potentially overcome several of these limitations that are inherent to the data and observational nature of the study