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GLP-1 medications have been shown to be effective options for individuals struggling with obesity and weight loss resistance

The concept of incretin effect was first proposed by Creutzfeldt in the 1970s (1, 2), based on the early observations that insulin secretion was two to three times higher after oral glucose intake than that after an isocaloric intravenous glucose administration (35)

2024;15:e00722

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These are called bellwether trials. The courts goal is that these few trials can result in a settlement program without having to hold trials for each of the thousands of cases that are filed