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These results indicate that exendin 939 does not share a binding site with CAP and inhibits TRPV1 activation by interacting noncompetitively with CAP
(2011) Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide, Biochim Biophys Acta

Accordingly, these patients should be evaluated for orthostatic hypotension before starting therapy with a SGLT2i [11]
